SCHEMBL23055306

SCHEMBL23055306

[N-]=[N+]=NCCCOCCC(=O)NCC#Cc1cn(C2CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.50
▸ POLA1 P09884 1/20 0.50
▸ POLD1 P28340 1/20 0.50
▸ P2RY2 P41231 1/20 0.45
▸ P2RY6 Q15077 1/20 0.45
▸ TYMS P04818 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26779532 0.91 POLB (0.47) POLBPOLA1POLD1
SCHEMBL20417783 0.86 POLB (0.51) POLBPOLA1POLD1
SCHEMBL2293561 0.86 POLB (0.51) POLBPOLA1POLD1
SCHEMBL18844329 0.86 POLB (0.51) POLBPOLA1POLD1
SCHEMBL23055192 0.85 TYMS (0.48) POLBPOLA1POLD1P2RY2P2RY6
SCHEMBL15115325 0.84 POLB (0.49) POLBPOLA1POLD1
SCHEMBL2301090 0.84 POLB (0.52) POLBPOLA1POLD1
SCHEMBL22598325 0.84 POLB (0.49) POLBPOLA1POLD1TYMS
SCHEMBL20417309 0.84 POLB (0.47) POLBPOLA1POLD1
SCHEMBL20417315 0.84 POLB (0.47) POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814675-B2 Edge sequencing with an immobilized translocator ROBERT BOSCH GMBH (DE) 2023-11-14 — — US disclosed
US-20210062255-A1 EDGE SEQUENCING WITH AN IMMOBILIZED TRANSLOCATOR ROBERT BOSCH GMBH (DE) 2021-03-04 — — US disclosed
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