⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055566 | 0.87 | — | — | |
| SCHEMBL23055903 | 0.86 | PRMT5 (0.34) | — | |
| SCHEMBL23055862 | 0.86 | PARP14 (0.32) | — | |
| SCHEMBL23055446 | 0.86 | — | — | |
| SCHEMBL23055393 | 0.85 | PRMT5 (0.34) | — | |
| SCHEMBL23055365 | 0.85 | TNF (0.31) | — | |
| SCHEMBL23055413 | 0.84 | LMNA (0.33) | — | |
| SCHEMBL23055624 | 0.84 | PRKCQ (0.34) | — | |
| SCHEMBL23055477 | 0.84 | IKZF2 (0.30) | — | |
| SCHEMBL23055574 | 0.84 | PRMT5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20210061761-A1 | MODULATORS OF COMPLEX I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-04 | — | — | US | disclosed |