Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057209 | 0.88 | L3MBTL1 (0.45) | KEAP1L3MBTL1PKMMCOLN3NPSR1 | |
| SCHEMBL23057051 | 0.86 | L3MBTL1 (0.43) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057120 | 0.86 | MEN1 (0.53) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057084 | 0.86 | L3MBTL1 (0.43) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057265 | 0.86 | MEN1 (0.53) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057203 | 0.86 | MAPK1 (0.45) | KEAP1L3MBTL1PKMMCOLN3NPSR1 | |
| SCHEMBL23057240 | 0.83 | L3MBTL1 (0.40) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057174 | 0.83 | L3MBTL1 (0.41) | KEAP1L3MBTL1PKMMCOLN3NPSR1 | |
| SCHEMBL23057216 | 0.83 | L3MBTL1 (0.40) | L3MBTL1PKMMCOLN3NPSR1MAPT | |
| SCHEMBL23057155 | 0.83 | L3MBTL1 (0.40) | KEAP1L3MBTL1PKMMCOLN3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |