SCHEMBL23057564

SCHEMBL23057564

Bc1c(F)cc(P)c(F)c1OC(=O)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.33
▸ ALOX15 P16050 1/20 0.31
▸ GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23057573 0.87 ELANE (0.36) ELANEALOX15GAA
SCHEMBL22381449 0.78 GAA (0.37) ELANEALOX15GAA
SCHEMBL22381458 0.77 ELANE (0.33) ELANEALOX15
SCHEMBL12213944 0.75 MAPT (0.42) ELANEALOX15GAA
SCHEMBL22381468 0.73 MAPT (0.37) ELANEALOX15GAA
SCHEMBL26144736 0.71 ELANE (0.30) ELANE
SCHEMBL11915792 0.70 ELANE (0.42) ELANEALOX15GAA
SCHEMBL17662449 0.70 ELANE (0.40) ELANEALOX15GAA
SCHEMBL19105004 0.69 ELANE (0.37) ELANEALOX15GAA
SCHEMBL25812803 0.68 GAA (0.33) ELANEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793895-B2 Residualizing linkers and uses thereof CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION 2023-10-24 — — US disclosed
US-20210060190-A1 RESIDUALIZING LINKERS AND USES THEREOF CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) 2021-03-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210060190-A1 RESIDUALIZING LINKERS AND USES THEREOF CD44, CD47, MTCL3 ELANE 3316/4885ALOX15 1362/4885GAA 541/4885
US-11793895-B2 Residualizing linkers and uses thereof CD44, CD47, MTCL3 ELANE 3316/4885ALOX15 1362/4885GAA 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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