Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12213944 | 0.89 | MAPT (0.42) | ELANEGAAKDM4EALDH1A1MAPT | |
| SCHEMBL23057573 | 0.81 | ELANE (0.36) | ELANEGAAKDM4EALDH1A1MAPT | |
| SCHEMBL12342059 | 0.79 | KDM4E (0.42) | GAAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL22381468 | 0.79 | MAPT (0.37) | ELANEGAAKDM4EALDH1A1MAPT | |
| SCHEMBL22381458 | 0.77 | ELANE (0.33) | ELANEKDM4EALDH1A1MAPTHTT | |
| SCHEMBL11915792 | 0.76 | ELANE (0.42) | ELANEGAAALOX15ADRB2ADRA2A | |
| SCHEMBL19105012 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1MAPTHTTALOX15 | |
| SCHEMBL21503687 | 0.76 | ELANE (0.48) | ELANEALOX15CES2CES1ADRB2 | |
| SCHEMBL17662449 | 0.76 | ELANE (0.40) | ELANEGAAALDH1A1ALOX15CES2 | |
| SCHEMBL18211365 | 0.75 | ELANE (0.39) | ELANEMAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399515-A1 | PHTHALOCYANINE DYE COMPOUNDS, CONJUGATES AND METHODS OF USE THEREOF | Rakuten Medical, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-05-25 | — | — | US | disclosed |
| US-9862682-B2 | Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof | BroadPharm (US) | 2018-01-09 | — | — | US | disclosed |
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | BroadPharm (US) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ABL1, EGFR, ALB | ELANE 848/4885GAA 930/4885KDM4E 779/4885 |
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | CTSA, CTSS, CTSV | ELANE 1019/4885GAA 15/4885KDM4E 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.