Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040134 | 1.00 | MEN1 (0.46) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL23040133 | 1.00 | MEN1 (0.46) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL23039954 | 0.90 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL13733686 | 0.90 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL23058774 | 0.90 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL23039956 | 0.90 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30521710 | 0.89 | MEN1 (0.47) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733682 | 0.89 | MEN1 (0.47) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733690 | 0.89 | MEN1 (0.47) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL13908363 | 0.85 | KMT2A (0.51) | MEN1KMT2APOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041588-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-03-04 | — | — | WO | disclosed |