Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759421 | 1.00 | KMT2A (0.51) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL30295062 | 0.92 | KMT2A (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23058774 | 0.88 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23039954 | 0.88 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23039956 | 0.88 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL13733686 | 0.88 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733682 | 0.87 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733690 | 0.87 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL30521710 | 0.87 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23058787 | 0.85 | MEN1 (0.46) | KMT2AMEN1L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101404987-A | Use of sulfonamide derivatives for the treatment of disorders of the surrogate and nervous systems | SMITHKLINE BEECHAM CORP (US) | 2009-04-08 | — | — | CN | disclosed |
| US-20090069302-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-12 | — | — | US | disclosed |
| WO-2007127505-A2 | USE OF SULFONAMIDE DERIVATIVES IN THE TREATMENT OF DISORDERS OF THE METABOLISM AND THE NERVOUS SYSTEM | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069302-A1 | CHEMICAL COMPOUNDS | TBXA2R, PDE4D, PDE4A | KMT2A 3729/4885MEN1 2095/4885L3MBTL1 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.