Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.41 |
| ▸ | MTOR | P42345 | 9/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15353802 | 0.88 | ALDH1A1 (0.47) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL15354465 | 0.88 | ALDH1A1 (0.49) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL23059291 | 0.77 | KDM4E (0.46) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL23059277 | 0.75 | ADORA2A (0.33) | KDM4E | |
| SCHEMBL23059275 | 0.75 | ADORA2A (0.33) | KDM4E | |
| SCHEMBL23059283 | 0.75 | ADORA2A (0.33) | KDM4E | |
| SCHEMBL179448 | 0.74 | PIK3CA (0.56) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL179421 | 0.74 | PIK3CA (0.56) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL179420 | 0.74 | PIK3CA (0.56) | KMT2AALDH1A1HPGDKDM4EGLA | |
| SCHEMBL23059281 | 0.73 | PDE8B (0.40) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060022-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | INFINITY PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060022-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | PIK3CA, MCL1, PIK3CB | KMT2A 1258/4885ALDH1A1 3671/4885HPGD 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.