SCHEMBL23059622

SCHEMBL23059622

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nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12441729 1.00 KMT2A (0.31) KMT2A
SCHEMBL25591250 0.89
SCHEMBL19223894 0.86 KMT2A (0.32) KMT2A
SCHEMBL21078748 0.86 KMT2A (0.32) KMT2A
SCHEMBL13212203 0.82 KMT2A (0.30) KMT2A
SCHEMBL19772872 0.82 KMT2A (0.32) KMT2A
SCHEMBL24044261 0.82 LMNA (0.33) KMT2A
SCHEMBL25594364 0.82
SCHEMBL6271209 0.82 KDM4E (0.32)
SCHEMBL25938423 0.80 KMT2A (0.34) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021038125-A2 CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES MEDICORTEX FINLAND OY (FI) 2021-03-04 WO disclosed