SCHEMBL2305979

SCHEMBL2305979

C=CC(O)(CC)COCCO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
THRB P10828 2/20 0.37
TSHR P16473 3/20 0.37
MAPK1 P28482 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419452 0.83 TSHR (0.36) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL29419450 0.80 TSHR (0.33) TSHRMAPK1MEN1KMT2A
SCHEMBL29419453 0.79 TSHR (0.32) TSHRMAPK1MEN1KMT2A
SCHEMBL1548104 0.76 TSHR (0.41) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL4177702 0.74
SCHEMBL29046448 0.73 MEN1 (0.44) ALDH1A1THRBTSHRMAPK1MEN1
SCHEMBL5191390 0.73 ALDH1A1 (0.48) ALDH1A1THRBTSHRMAPK1MEN1
SCHEMBL1790811 0.72 MEN1 (0.48) ALDH1A1THRBTSHRMAPK1MEN1
SCHEMBL27709628 0.71 ALDH1A1 (0.46) ALDH1A1THRBTSHRMAPK1MEN1
SCHEMBL16672209 0.70 ALDH1A1 (0.50) ALDH1A1THRBTSHRMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350386-A1 METHOD FOR MANUFACTURING SHEET MATERIAL Filsen Pty Ltd (AU) 2011-08-03 EP disclosed
WO-2009043110-A1 METHOD FOR MANUFACTURING SHEET MATERIAL FILSEN PTY LTD (AU) 2009-04-09 WO disclosed
EP-1278781-A4 RADIATION POLYMERISABLE COMPOSITIONS BALLINA PTY LTD (AU) 2005-01-26 EP disclosed
US-6767933-B2 CONTAINING CHARGE TRANSFER COMPOUND BALLINA PTY LTD (AU) 2004-07-27 US disclosed
US-20040044094-A1 Radiation polymerisable compositions having accelerated cure GARNETT JOHN LYNDON (AU) 2004-03-04 US disclosed
EP-1332187-A1 RADIATION POLYMERISABLE COMPOSITIONS HAVING ACCELERATED CURE Garnett, John Lyndon (AU) 2003-08-06 EP disclosed
US-20030073755-A1 Radiation polymerisable compositions BALLINA PTY. LTD. (AU) 2003-04-17 US disclosed
WO-2003018642-A1 PREPARATION OF POLYMER COMPOSITES GARNETT JOHN LYNDON (AU) 2003-03-06 WO disclosed
EP-1278781-A1 RADIATION POLYMERISABLE COMPOSITIONS Ballina Pty. Ltd. (AU) 2003-01-29 EP disclosed
WO-2002020677-A1 RADIATION POLYMERISABLE COMPOSITIONS HAVING ACCELERATED CURE GARNETT JOHN LYNDON (AU) 2002-03-14 WO disclosed
WO-2001025288-A1 RADIATION POLYMERISABLE COMPOSITIONS BALLINA PTY LTD (AU) 2001-04-12 WO disclosed
EP-0618237-B1 Polymerization process FUSION UV SYS INC (US) 1998-09-02 EP disclosed
US-5446073-A Photopolymerization process employing a charge transfer complex without a photoinitiator FUSION SYSTEMS CORPORATION (US) 1995-08-29 US disclosed
EP-0618237-A1 Polymerization process FUSION SYSTEMS CORPORATION (US) 1994-10-05 EP disclosed