Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPM1 | P06748 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042321 | 0.83 | CYP11B1 (0.38) | MEN1KMT2AMAPTCYP11B1CYP11B2 | |
| SCHEMBL29612462 | 0.82 | NPM1 (0.38) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL23042404 | 0.82 | NPM1 (0.38) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL30838359 | 0.79 | KDM4E (0.40) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL24668140 | 0.77 | SNCA (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL15112680 | 0.75 | MAPT (0.55) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL29729492 | 0.75 | MAPT (0.55) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL20987182 | 0.75 | MAPT (0.42) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL29729386 | 0.75 | MAPT (0.42) | MEN1KMT2AALDH1A1RAB9ANPM1 | |
| SCHEMBL23042350 | 0.72 | CYP11B2 (0.43) | MEN1KMT2AALDH1A1RAB9ANPM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301357-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns Pharmaceuticals, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187403-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | TERNS PHARMACEUTICALS, INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| WO-2022187403-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | TERNS PHARMACEUTICALS, INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| EP-4017875-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns Pharmaceuticals, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021041237-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns, Inc. (US) | 2021-03-04 | — | — | WO | disclosed |