Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphocholine SCHEMBL3960127 | 0.93 | SMN1; SMN2 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL3954612 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL3958479 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL27650430 | 0.85 | FABP3 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL28083493 | 0.85 | FABP3 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL8790092 | 0.85 | FABP3 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL28083428 | 0.84 | S1PR1 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| SCHEMBL993163 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| SCHEMBL3525643 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 | |
| Phosphocholine SCHEMBL1557025 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2NR5A2NR5A1FABP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350662-A1 | COMBINATION OF SPLA2 ACTIVITY AND OXPL/APOB CARDIOVASCULAR RISK FACTORS FOR THE DIAGNOSIS/PROGNOSIS OF A CARDIOVASCULAR DISEASE/EVENT | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010037860-A1 | COMBINATION OF SPLA2 ACTIVITY AND OXPL/APOB CARDIOVASCULAR RISK FACTORS FOR THE DIAGNOSIS/PROGNOSIS OF A CARDIOVASCULAR DISEASE/EVENT. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-04-08 | — | — | WO | disclosed |