Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198346 | 0.98 | KEAP1 (0.48) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL23064483 | 0.98 | KEAP1 (0.48) | KEAP1MAPK1GAAHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL23064591 | 0.96 | KEAP1 (0.47) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL23064544 | 0.94 | PDCD1 (0.51) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL23064527 | 0.92 | KEAP1 (0.47) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL23064565 | 0.92 | PDCD1 (0.49) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL18701462 | 0.88 | HTR2C (0.50) | KEAP1MAPK1HTR1AADRA1BSLC6A2 | |
| SCHEMBL2913876 | 0.86 | PDCD1 (0.44) | KEAP1MAPK1GAAHTR1AADRA1B | |
| SCHEMBL11882582 | 0.85 | GRM2 (0.46) | MAPK1GAAHTR1AADRA1BPDCD1 | |
| SCHEMBL15834289 | 0.82 | HTR2C (0.51) | HTR1AADRA1BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788042-A1 | BCL-2 INHIBITORS | BeiGene, Ltd. (KY) | 2021-03-10 | — | — | EP | disclosed |