Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25943658 | 0.90 | KDM4E (0.55) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL23053099 | 0.89 | ALDH1A1 (0.70) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL23065639 | 0.80 | MEN1 (0.77) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL18812556 | 0.78 | MAPT (0.75) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL23065642 | 0.78 | KDM4E (0.64) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| Taiwanin E Methyl Ether SCHEMBL11954034 | 0.78 | MAPT (0.74) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| Taiwanin E Methyl Ether SCHEMBL30637589 | 0.78 | MAPT (0.74) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL18803393 | 0.77 | ALDH1A1 (0.64) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL23065641 | 0.76 | MAPT (0.56) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| Taiwanin E SCHEMBL15363973 | 0.76 | MEN1 (0.82) | KDM4EMAPTALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021037077-A1 | PATENTIFLORIN A ANALOGS AS ANTIVIRAL AGENTS | HONG KONG BAPTIST UNIVERSITY (CN) | 2021-03-04 | — | — | WO | disclosed |