⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748332 | 0.77 | — | — | |
| SCHEMBL27405755 | 0.75 | — | — | |
| SCHEMBL569861 | 0.74 | ALDH1A1 (0.52) | — | |
| SCHEMBL3652188 | 0.74 | ALDH1A1 (0.52) | — | |
| SCHEMBL17209104 | 0.74 | ALDH1A1 (0.41) | — | |
| Acrylamide SCHEMBL19713113 | 0.73 | ALDH1A1 (0.52) | — | |
| SCHEMBL6584842 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL9781272 | 0.73 | — | — | |
| SCHEMBL170266 | 0.72 | — | — | |
| SCHEMBL4243340 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034888-B2 | Substituted 2-imidazolidones and analogs | UNIVERSITE LAVAL (CA) | 2015-05-19 | — | — | US | claimed |
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | claimed |
| US-20120309777-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITE LAVAL (CA) | 2012-12-06 | — | — | US | claimed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | claimed |
| EP-1095044-A1 | PIPERAZYNIL PYRIMIDINE DIONE COMPOUNDS SELECTIVE FOR ADRENOCEPTORS | ABBOTT LABORATORIES (US) | 2001-05-02 | — | — | EP | disclosed |
| US-6166019-A | Piperazinyl pyrimidine dione compounds selective for adrenoceptors | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |
| US-6153614-A | Piperazinyl pyrimidine dione compounds selective for adrenoceptors | ABBOTT LABORATORIES (US) | 2000-11-28 | — | — | US | disclosed |
| WO-2000004027-A1 | PIPERAZYNIL PYRIMIDINE DIONE COMPOUNDS SELECTIVE FOR ADRENOCEPTORS | ABBOTT LABORATORIES (US) | 2000-01-27 | — | — | WO | disclosed |