⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022504 | 0.86 | — | — | |
| SCHEMBL6920725 | 0.86 | — | — | |
| SCHEMBL6919767 | 0.85 | — | — | |
| SCHEMBL1989485 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1988968 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1991970 | 0.84 | — | — | |
| SCHEMBL13580670 | 0.80 | HTR2C (0.45) | — | |
| SCHEMBL22996393 | 0.79 | — | — | |
| SCHEMBL31187351 | 0.77 | MAOA (0.74) | — | |
| SCHEMBL17541979 | 0.76 | MEN1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697636-B2 | Substituted benzamides | HOFFMANN-LA ROCHE INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20210061760-A1 | SUBSTITUTED BENZAMIDES | HOFFMANN LA ROCHE (US) | 2021-03-04 | — | — | US | disclosed |