SCHEMBL23067971

SCHEMBL23067971

CC(=O)N[C@@H]1CCC[C@H](C(=O)Nc2cc(-c3cc(F)c4ncn(C(C)C)c4c3)c(C)cn2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 20/20 1.00
CDK4 P11802 20/20 1.00
CCND1 P24385 20/20 1.00
CDK9 P50750 20/20 1.00
CCNA2 P20248 7/20 1.00
CDK2 P24941 7/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23068004 1.00 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL29788720 1.00 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL29788700 1.00 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL29788692 0.95 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL23067979 0.95 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL23067986 0.94 CCNT1 (0.90) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL29788730 0.93 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL23067950 0.93 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL29788670 0.93 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2
SCHEMBL23081086 0.92 CCNT1 (1.00) CCNT1CDK4CCND1CDK9CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673893-B2 CDK inhibitors and their use as pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED (US) 2023-06-13 US claimed
US-20230144528-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS, INCORPORATED 2023-05-11 US claimed
WO-2023056441-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2023-04-06 WO claimed
CN-114786673-A CDK inhibitors and their use as medicaments 普莱鲁德疗法有限公司 2022-07-22 CN claimed
US-20210070761-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED 2021-03-11 US claimed
US-12486277-B2 CDK inhibitors and their use as pharmaceuticals Prelude Therapeutis Incorporated (US) 2025-12-02 US disclosed
US-20230242543-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED 2023-08-03 US disclosed
US-20230242543-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED 2023-08-03 US disclosed
US-11673893-B2 CDK inhibitors and their use as pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED (US) 2023-06-13 US disclosed
US-11673893-B2 CDK inhibitors and their use as pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED (US) 2023-06-13 US disclosed
US-20230144528-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS, INCORPORATED 2023-05-11 US disclosed
US-20230144528-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS, INCORPORATED 2023-05-11 US disclosed
WO-2023056441-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2023-04-06 WO disclosed
US-20220324830-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS, INCORPORATED 2022-10-13 US disclosed
CN-114786673-A CDK inhibitors and their use as medicaments 普莱鲁德疗法有限公司 2022-07-22 CN disclosed
EP-4028005-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS Prelude Therapeutics, Incorporated (US) 2022-07-20 EP disclosed
WO-2021050824-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2021-03-18 WO disclosed
WO-2021050824-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2021-03-18 WO disclosed
US-20210070761-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED 2021-03-11 US disclosed
US-20210070761-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED 2021-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11673893-B2 CDK inhibitors and their use as pharmaceuticals CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885
US-20230144528-A1 CDK Inhibitors And Their Use As Pharmaceuticals CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885
US-20220324830-A1 CDK Inhibitors And Their Use As Pharmaceuticals CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885
US-12486277-B2 CDK inhibitors and their use as pharmaceuticals CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885
US-20230242543-A1 CDK Inhibitors And Their Use As Pharmaceuticals CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885
US-20210070761-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS CDK6, CDK3, CDK9 CCNT1 40/4885CDK4 10/4885CCND1 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.