SCHEMBL23069072

SCHEMBL23069072

O=C(NC(=O)Nc1ccc(C(=O)Oc2ccccc2)cc1)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.65
MEN1 O00255 5/20 0.65
ALDH1A1 P00352 2/20 0.58
HPGD P15428 2/20 0.58
EPHX2 P34913 3/20 0.54
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
SMN1; SMN2 Q16637 4/20 0.51
MAPT P10636 2/20 0.51
TAAR1 Q96RJ0 1/20 0.51
THRB P10828 1/20 0.51
TP53 P04637 1/20 0.50
EPHX1 P07099 1/20 0.50
TSHR P16473 1/20 0.50
CDK9 P50750 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PRSS1 P07477 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385558 0.93 KMT2A (0.69) KMT2AMEN1ALDH1A1HPGDEPHX2
SCHEMBL21810511 0.87 KMT2A (0.73) KMT2AMEN1ALDH1A1HPGDEPHX2
SCHEMBL30599809 0.86 EPHX2 (0.62) KMT2AMEN1EPHX2NPC1RAB9A
SCHEMBL4924025 0.84 MEN1 (0.65) KMT2AMEN1ALDH1A1HPGDEPHX2
SCHEMBL23069011 0.83 MEN1 (0.71) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL4911144 0.81 MAPT (0.66) KMT2AMEN1ALDH1A1HPGDNPC1
SCHEMBL11656439 0.81 SMN1; SMN2 (0.66) KMT2AMEN1ALDH1A1HPGDNPC1
SCHEMBL70034 0.80 PARP10 (0.70) KMT2AMEN1ALDH1A1HPGDRAB9A
SCHEMBL23069071 0.80 KMT2A (0.56) KMT2AMEN1ALDH1A1EPHX2NPC1
SCHEMBL11656020 0.80 ALDH1A1 (0.57) KMT2AMEN1ALDH1A1EPHX2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781029-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2023-10-10 US disclosed
EP-3790739-B1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2022-04-20 EP disclosed
EP-3790739-A1 HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2021-03-17 EP disclosed
US-20210071025-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-03-11 US disclosed