Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 11/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | MAG | P20916 | 1/20 | 0.36 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306939 | 1.00 | LGALS8 (0.42) | LGALS8TLR4SELPMAGSYNJ2 | |
| SCHEMBL2313099 | 0.84 | TLR4 (0.44) | TLR4SELP | |
| SCHEMBL2313867 | 0.83 | TLR4 (0.39) | LGALS8TLR4SELP | |
| SCHEMBL2310244 | 0.83 | TLR4 (0.50) | TLR4SELP | |
| SCHEMBL6565889 | 0.82 | TLR4 (0.49) | LGALS8TLR4SELP | |
| SCHEMBL6565888 | 0.82 | TLR4 (0.49) | LGALS8TLR4SELP | |
| SCHEMBL29608129 | 0.82 | TLR4 (0.45) | LGALS8TLR4SELP | |
| SCHEMBL9786197 | 0.82 | TLR4 (0.49) | LGALS8TLR4SELP | |
| SCHEMBL9786193 | 0.82 | TLR4 (0.49) | LGALS8TLR4SELP | |
| SCHEMBL2311527 | 0.81 | LGALS8 (0.47) | LGALS8MAG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |