⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192049 | 0.73 | — | — | |
| SCHEMBL8392179 | 0.73 | — | — | |
| SCHEMBL182083 | 0.71 | — | — | |
| SCHEMBL10788991 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL27974674 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL249929 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28456398 | 0.67 | — | — | |
| SCHEMBL57087 | 0.67 | — | — | |
| SCHEMBL28915963 | 0.65 | — | — | |
| Benzene SCHEMBL8002838 | 0.65 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324809-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS AND USES THEREOF | SALZMAN GROUP LTD (IL) | 2022-10-13 | — | — | US | disclosed |
| EP-4025300-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | Salzman Group Ltd. (IL) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021044413-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | SALZMAN GROUP LTD. (IL) | 2021-03-11 | — | — | WO | disclosed |