SCHEMBL249929

SCHEMBL249929

C=C[CH]C(C)(C)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11233621 0.77
SCHEMBL182083 0.73
SCHEMBL1828790 0.73
SCHEMBL27974674 0.72 TSHR (0.43)
SCHEMBL11664608 0.71 TSHR (0.37)
SCHEMBL6192049 0.69
Hydrochloric Acid SCHEMBL28456398 0.69
SCHEMBL8392179 0.69
SCHEMBL23069458 0.67
SCHEMBL3049765 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5352846-A Hydrogenating and isomerizing isopentenes, etherifying, distilling INSTITUT FRANCAIS DU PETROLE (FR) 1994-10-04 US claimed
US-20140179811-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS HICKORY SPRINGS MFG CO (US) 2014-06-26 US disclosed
US-8575225-B2 Use of low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates as flame retardants in polyurethane or polyisocyanurate foams HICKORY SPRINGS MANUFACTURING COMPANY (US) 2013-11-05 US disclosed
US-8350074-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2013-01-08 US disclosed
US-8143433-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2012-03-27 US disclosed
US-20120004438-A1 Low Triphenylphosphate, High Phosphorous Content Isopropyl Phenyl Phosphates With High Ortho Alkylation ALBEMARLE CORPORATION (US) 2012-01-05 US disclosed
US-7943601-B2 2-methylene-20-methyl-19,24,25,26,27-pentanor-vitamin D analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-05-17 US disclosed
EP-2004597-B1 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS WITH A 1,1-DIMETHYLPROPYL SIDE CHAIN WISCONSIN ALUMNI RES FOUND (US) 2011-01-26 EP disclosed
EP-2240438-A1 2-METHYLENE-20-METHYL-19,24,25,26,27-PENTANOR-VITAMIN D ANALOGS Wisconsin Alumni Research Foundation (US) 2010-10-20 EP disclosed
US-7763598-B2 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-07-27 US disclosed
WO-2009086440-A1 2-METHYLENE-20-METHYL-19,24,25,26,27-PENTANOR-VITAMIN D ANALOGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-07-09 WO disclosed
US-20090170822-A1 2-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs WISCONSIN ALUMNI RESEARCH FOUNDATION 2009-07-02 US disclosed
EP-2021347-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION Albermarle Corporation (US) 2009-02-11 EP disclosed
EP-2004597-A2 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS WITH A 1,1-DIMETHYLPROPYL SIDE CHAIN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-12-24 EP disclosed
WO-2008118695-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARLE CORPORATION (US) 2008-10-02 WO disclosed
WO-2008118699-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS ALBEMARLE CORPORATION (US) 2008-10-02 WO disclosed
WO-2008023278-A2 1ALPHA-HYDROXY-2- (3 ' -HYDROXYPROPYLIDENE) -19-N0R- VITAMIN D COMPOUNDS WITH A 1,1-DIMETHYLPROPYL SIDE CHAIN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-02-28 WO disclosed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO disclosed
US-20070238703-A1 1alpha-Hydroxy-2-(3'-Hydroxypropylidene)-19-Nor-Vitamin D Compounds with a 1,1-Dimethylpropyl Side Chain WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-10-11 US disclosed
US-6013791-A Process for the preparation of 4-(formylthio)-azetidin-2-one derivatives and penem derivatives SMITHKLINE BEECHAM P.L.C. (GB) 2000-01-11 US disclosed