⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121203 | 0.79 | — | — | |
| SCHEMBL2121208 | 0.79 | — | — | |
| SCHEMBL17049219 | 0.78 | — | — | |
| SCHEMBL57503 | 0.78 | — | — | |
| SCHEMBL56450 | 0.74 | — | — | |
| SCHEMBL6083123 | 0.72 | — | — | |
| SCHEMBL276265 | 0.72 | — | — | |
| SCHEMBL713895 | 0.72 | — | — | |
| SCHEMBL22804132 | 0.72 | — | — | |
| SCHEMBL7753360 | 0.72 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324809-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS AND USES THEREOF | SALZMAN GROUP LTD (IL) | 2022-10-13 | — | — | US | disclosed |
| EP-4025300-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | Salzman Group Ltd. (IL) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021044413-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | SALZMAN GROUP LTD. (IL) | 2021-03-11 | — | — | WO | disclosed |