Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069521 | 1.00 | TACR1 (0.51) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL29664049 | 0.96 | ITGB3 (0.50) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL23069604 | 0.96 | ITGB3 (0.50) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL17685870 | 0.96 | ITGB3 (0.50) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL23069517 | 0.96 | ITGB3 (0.52) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL23069519 | 0.96 | ITGB3 (0.52) | TACR1MMEECE1ITGB3ITGA2B | |
| SCHEMBL29774411 | 0.94 | TACR1 (0.51) | TACR1CTSLCTSBCTSSF2 | |
| SCHEMBL25471765 | 0.94 | TACR1 (0.53) | TACR1CTSLCTSBCTSSF2 | |
| SCHEMBL25471864 | 0.94 | TACR1 (0.50) | TACR1CTSLCTSBCTSSF2 | |
| SCHEMBL25471768 | 0.94 | TACR1 (0.50) | TACR1CTSLCTSBCTSSF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4025200-A1 | LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF | Neuroderm Ltd (IL) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021044420-A1 | LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF | NEURODERM, LTD. (IL) | 2021-03-11 | — | — | WO | disclosed |