SCHEMBL23070366

SCHEMBL23070366

CCCCOc1cc(CO)c(OCCCC)cc1CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 1/20 0.46
PSEN2 P49810 1/20 0.46
APH1B Q8WW43 1/20 0.46
NCSTN Q92542 1/20 0.46
APH1A Q96BI3 1/20 0.46
PSENEN Q9NZ42 1/20 0.46
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
LTA4H P09960 1/20 0.38
NR5A1 Q13285 1/20 0.38
ESR1 P03372 1/20 0.38
TSHR P16473 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225200 0.92 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19870481 0.92 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7774230 0.92 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30775067 0.88 PSEN1 (0.48) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7777616 0.84 PSEN1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7027038 0.83 ESR1 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30966558 0.83 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14607916 0.81 MAPT (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL11356391 0.81 CNR2 (0.50) LTA4HNR5A1ESR1TSHRRAB9A
SCHEMBL12656326 0.81 PSEN1 (0.38) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12366535-B2 Tautomeric sensing using a covalent organic framework NORTHWESTERN UNIVERSITY (US) 2025-07-22 US disclosed
US-20220341851-A1 TAUTOMERIC SENSING USING A COVALENT ORGANIC FRAMEWORK GEORGIA TECH RESEARCH CORPORATION 2022-10-27 US disclosed
WO-2021046516-A1 TAUTOMERIC SENSING USING A COVALENT ORGANIC FRAMEWORK NORTHWESTERN UNIVERSITY (US) 2021-03-11 WO disclosed