Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225200 | 0.91 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19870481 | 0.91 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7774230 | 0.91 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1030141 | 0.91 | ALDH1A1 (0.45) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL6132178 | 0.91 | ALDH1A1 (0.45) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL30775067 | 0.88 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6303236 | 0.85 | HTR2A (0.45) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL16226635 | 0.85 | HTR2A (0.45) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL8509518 | 0.85 | HTR2A (0.45) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL27574915 | 0.84 | CYP1A2 (0.42) | MAPTALDH1A1THRBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704094-B1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2001-08-08 | — | — | EP | disclosed |
| US-5514878-A | Polymers for electroluminescent devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0704094-A1 | POLYMERS FOR OPTICAL DEVICES | Cambridge Display Technology Limited (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029883-A1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |