Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654165 | 0.89 | GLS (1.00) | GLS | |
| SCHEMBL19454305 | 0.87 | GLS (0.90) | GLS | |
| SCHEMBL17654132 | 0.87 | GLS (1.00) | GLS | |
| SCHEMBL17654078 | 0.86 | GLS (0.93) | GLS | |
| SCHEMBL12244625 | 0.85 | GLS (0.73) | GLS | |
| SCHEMBL17654103 | 0.85 | GLS (1.00) | GLS | |
| SCHEMBL28452921 | 0.84 | GLS (0.90) | GLS | |
| SCHEMBL26706154 | 0.84 | GLS (0.89) | GLS | |
| SCHEMBL31550406 | 0.84 | GLS (0.84) | GLS | |
| SCHEMBL17654174 | 0.83 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042723-A1 | GLUTAMINASE GLS1 INHIBITOR CONTAINING TRIAZOLE STRUCTURE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |
| CN-110746416-A | Glutaminase GLS1 inhibitor containing triazole structure or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2020-02-04 | — | — | CN | disclosed |