Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CTPS1 | P17812 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545066 | 0.77 | KMT2A (0.46) | MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL468025 | 0.76 | KMT2A (0.45) | MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20530847 | 0.73 | MCHR1 (0.33) | CTPS1MAPTKDM4E | |
| SCHEMBL25427575 | 0.71 | HSD17B10 (0.61) | SLC6A3MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL937324 | 0.70 | — | — | |
| SCHEMBL10517711 | 0.69 | — | — | |
| SCHEMBL25426497 | 0.69 | PGK1 (0.47) | SLC6A3SMN1; SMN2 | |
| SCHEMBL1751317 | 0.69 | — | — | |
| SCHEMBL1990600 | 0.69 | — | — | |
| SCHEMBL15349311 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043077-A1 | SUBSTITUTED PYRAZINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-03-11 | — | — | WO | disclosed |