Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710336 | 0.84 | PTPN11 (0.38) | PTPN11EGFRKCNH2 | |
| SCHEMBL23084058 | 0.79 | PTPN11 (0.56) | PTPN11EGFRKCNH2 | |
| SCHEMBL29446723 | 0.79 | PTPN11 (0.56) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083605 | 0.79 | PTPN11 (0.56) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083633 | 0.79 | PTPN11 (0.56) | PTPN11EGFRKCNH2 | |
| SCHEMBL29070211 | 0.78 | PTPN11 (0.41) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083664 | 0.77 | PTPN11 (0.52) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083793 | 0.77 | PTPN11 (0.52) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083732 | 0.77 | PTPN11 (0.52) | PTPN11EGFRKCNH2 | |
| SCHEMBL23083510 | 0.77 | PTPN11 (0.33) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043077-A1 | SUBSTITUTED PYRAZINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-03-11 | — | — | WO | disclosed |