Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073026 | 0.93 | BRD4 (0.40) | BRD4P2RX7 | |
| SCHEMBL23473027 | 0.90 | BRD4 (0.46) | BRD4P2RX7GRIN1GRIN2B | |
| SCHEMBL23072972 | 0.89 | BRD4 (0.45) | BRD4 | |
| SCHEMBL18164205 | 0.88 | BRD4 (0.43) | BRD4GRIN1GRIN2B | |
| SCHEMBL23073194 | 0.85 | BRD4 (0.34) | BRD4 | |
| SCHEMBL23073201 | 0.84 | BRD4 (0.40) | BRD4GRIN1GRIN2B | |
| SCHEMBL23072953 | 0.82 | BRD4 (0.49) | BRD4 | |
| SCHEMBL18164208 | 0.81 | BRD4 (0.43) | BRD4P2RX7 | |
| SCHEMBL18152880 | 0.78 | BRD4 (0.45) | BRD4GRIN1GRIN2B | |
| SCHEMBL23073001 | 0.78 | BRD4 (0.43) | BRD4P2RX7GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |