Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164212 | 0.88 | BRD4 (0.49) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23073194 | 0.86 | BRD4 (0.34) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL23073026 | 0.84 | BRD4 (0.40) | BRD4CREBBP | |
| SCHEMBL23073030 | 0.84 | BRD4 (0.44) | BRD4GRIN1GRIN2B | |
| SCHEMBL23073054 | 0.77 | BRD4 (0.44) | BRD4 | |
| SCHEMBL18164209 | 0.76 | BRD4 (0.41) | BRD4BRD9BRD2CREBBP | |
| SCHEMBL23073186 | 0.75 | BRD4 (0.36) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL18164213 | 0.74 | BRD4 (0.45) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23473027 | 0.73 | BRD4 (0.46) | BRD4GRIN1GRIN2B | |
| SCHEMBL23072953 | 0.73 | BRD4 (0.49) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |