Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164242 | 0.85 | HPGD (0.39) | BRD4TSHRHPGDMEN1KMT2A | |
| SCHEMBL18152893 | 0.84 | BRD4 (0.54) | BRD4 | |
| SCHEMBL18528948 | 0.82 | BRD4 (0.60) | BRD4 | |
| SCHEMBL23073149 | 0.81 | BRD4 (0.56) | BRD4TSHRHPGDMEN1KMT2A | |
| SCHEMBL23473063 | 0.76 | BRD4 (0.49) | BRD4 | |
| SCHEMBL23473011 | 0.76 | BRD4 (0.45) | BRD4 | |
| SCHEMBL23473022 | 0.76 | BRD4 (0.41) | BRD4 | |
| SCHEMBL23073126 | 0.76 | BRD4 (0.47) | BRD4 | |
| SCHEMBL23473025 | 0.76 | BRD4 (0.49) | BRD4 | |
| SCHEMBL23073066 | 0.76 | BRD4 (0.49) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |