Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152893 | 0.82 | BRD4 (0.54) | BRD4 | |
| SCHEMBL18152713 | 0.82 | BRD4 (0.46) | BRD4BRD9 | |
| SCHEMBL23073045 | 0.81 | BRD4 (0.49) | BRD4TSHRHPGDMEN1KMT2A | |
| SCHEMBL18528948 | 0.80 | BRD4 (0.60) | BRD4 | |
| SCHEMBL18538433 | 0.75 | BRD4 (0.55) | BRD4 | |
| SCHEMBL22516869 | 0.73 | BRD4 (0.54) | BRD4HPGD | |
| SCHEMBL18152792 | 0.72 | BRD4 (0.65) | BRD4 | |
| SCHEMBL23072940 | 0.72 | BRD4 (0.61) | BRD4 | |
| SCHEMBL18152675 | 0.71 | BRD4 (0.69) | BRD4 | |
| SCHEMBL23073072 | 0.71 | BRD4 (0.49) | BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831383-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |