Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073236 | 0.87 | BRD4 (0.51) | BRD4BRD2BRD3BRDT | |
| SCHEMBL18164491 | 0.80 | BRD4 (0.41) | BRD4BRD2BRD3BRDT | |
| SCHEMBL23073104 | 0.79 | BRD4 (0.44) | BRD4BRD2BRD3BRDT | |
| SCHEMBL18152758 | 0.79 | BRD4 (0.44) | BRD4BRD2BRD3BRDT | |
| SCHEMBL23072996 | 0.77 | EPAS1 (0.43) | BRD4 | |
| SCHEMBL15549928 | 0.76 | BRD4 (0.53) | BRD4BRD2BRD3BRDT | |
| SCHEMBL19930740 | 0.76 | BRD4 (0.53) | BRD4BRD2BRD3BRDT | |
| SCHEMBL15552702 | 0.74 | HSPB1 (0.55) | BRD4BRD2BRD3BRDT | |
| SCHEMBL16651798 | 0.74 | BRD4 (0.62) | BRD4BRD2BRD3BRDT | |
| SCHEMBL25042168 | 0.73 | BRD4 (0.53) | BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |