SCHEMBL23073121

SCHEMBL23073121

CSNc1cc(-c2cc(C)c(=O)n(C)c2)cc2c1nc(C)n2Cc1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23073135 0.91 BRD4 (0.53) BRD4
SCHEMBL23072992 0.90 BRD4 (0.48) BRD4
SCHEMBL23073184 0.90 BRD4 (0.45) BRD4
SCHEMBL23073001 0.90 BRD4 (0.43) BRD4
SCHEMBL18538433 0.88 BRD4 (0.55) BRD4
SCHEMBL18152876 0.86 BRD4 (0.50) BRD4
SCHEMBL18538405 0.86 BRD4 (0.59) BRD4
SCHEMBL18164198 0.86 BRD4 (0.47) BRD4
SCHEMBL23073126 0.86 BRD4 (0.47) BRD4
SCHEMBL23073145 0.85 BRD4 (0.47) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283077-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2021-03-10 EP disclosed