SCHEMBL23073145

SCHEMBL23073145

CSNc1nc(-c2cc(C)c(=O)n(C)c2)cc2c1nc(C)n2Cc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18152829 0.87 BRD4 (0.47) BRD4
SCHEMBL18164467 0.86 BRD4 (0.46) BRD4
SCHEMBL23473058 0.85 BRD4 (0.46) BRD4
SCHEMBL23073121 0.85 BRD4 (0.48) BRD4
SCHEMBL23073207 0.81 BRD4 (0.42) BRD4
SCHEMBL18538433 0.81 BRD4 (0.55) BRD4
SCHEMBL18164323 0.80 BRD4 (0.47) BRD4
SCHEMBL18152775 0.78 BRD4 (0.52) BRD4
SCHEMBL18164334 0.77 BRD4 (0.44) BRD4
SCHEMBL23473028 0.77 BRD4 (0.51) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3831383-A1 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2021-06-09 EP disclosed
EP-3283077-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2021-03-10 EP disclosed