Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164463 | 0.87 | BRD4 (0.43) | BRD4PKMPKLR | |
| SCHEMBL23073145 | 0.81 | BRD4 (0.47) | BRD4 | |
| SCHEMBL23072963 | 0.81 | BRD4 (0.42) | BRD4 | |
| SCHEMBL18164485 | 0.80 | BRD4 (0.43) | BRD4 | |
| SCHEMBL18164344 | 0.79 | BRD4 (0.50) | BRD4 | |
| SCHEMBL18164266 | 0.77 | BRD4 (0.43) | BRD4 | |
| SCHEMBL23072972 | 0.76 | BRD4 (0.45) | BRD4 | |
| SCHEMBL18164276 | 0.74 | BRD4 (0.47) | BRD4PKMPKLR | |
| SCHEMBL23073066 | 0.74 | BRD4 (0.49) | BRD4PKMPKLR | |
| SCHEMBL18164326 | 0.72 | CREBBP (0.55) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |