Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297327 | 0.81 | HCAR2 (0.50) | KDM4EALDH1A1KMT2ACYP11B2CHEK1 | |
| SCHEMBL14754890 | 0.78 | KMT2A (0.44) | KDM4EALDH1A1KMT2ACYP11B2CHEK1 | |
| SCHEMBL20987766 | 0.77 | KMT2A (0.39) | KDM4EALDH1A1KMT2ACYP11B2CHEK1 | |
| SCHEMBL14752177 | 0.77 | ESRRG (0.40) | KDM4EALDH1A1KMT2ACYP11B2CHEK1 | |
| SCHEMBL14865309 | 0.73 | KDM4E (0.70) | KDM4EALDH1A1CYP11B2SIRT2SIRT1 | |
| SCHEMBL30239217 | 0.73 | KDM4E (0.70) | KDM4EALDH1A1CYP11B2SIRT2SIRT1 | |
| SCHEMBL7662074 | 0.72 | KMT2A (0.45) | KDM4EALDH1A1KMT2ACYP11B2MEN1 | |
| SCHEMBL14429888 | 0.71 | ALDH1A1 (0.72) | KDM4EALDH1A1KMT2ACYP11B2HTT | |
| SCHEMBL30478431 | 0.71 | ALDH1A1 (1.00) | KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL185398 | 0.71 | ALDH1A1 (1.00) | KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513793-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2021-03-10 | — | — | EP | disclosed |