Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 15/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23078247 | 0.91 | CD274 (0.47) | CD274PDCD1MCL1MRGPRX4 | |
| SCHEMBL23078790 | 0.90 | PDCD1 (0.49) | CD274PDCD1 | |
| SCHEMBL23078706 | 0.89 | CD274 (0.52) | CD274PDCD1MCL1 | |
| SCHEMBL23078779 | 0.87 | PDCD1 (0.51) | CD274PDCD1 | |
| SCHEMBL23078503 | 0.85 | PDCD1 (0.52) | CD274PDCD1 | |
| SCHEMBL23078186 | 0.84 | PDCD1 (0.44) | CD274PDCD1 | |
| SCHEMBL23078636 | 0.84 | PDCD1 (0.46) | CD274PDCD1MCL1PTGER1PTGER4 | |
| SCHEMBL23078705 | 0.84 | PDCD1 (0.47) | CD274PDCD1PTGER1PTGER4PTGER3 | |
| SCHEMBL23078357 | 0.84 | PDCD1 (0.44) | CD274PDCD1 | |
| SCHEMBL23078761 | 0.83 | CD274 (0.50) | CD274PDCD1MCL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |