Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20841237 | 0.84 | RECQL (0.52) | RECQLSLC6A5GAAFAAHTSHR | |
| SCHEMBL16217880 | 0.84 | RECQL (0.60) | RECQLSLC6A5GAAFAAHTSHR | |
| SCHEMBL12962267 | 0.82 | PAOX (0.53) | CASP2ADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL26254307 | 0.81 | SLC6A5 (0.54) | SLC6A5EPHX2CASP2FAAHKDM4E | |
| SCHEMBL28444812 | 0.80 | PAOX (0.57) | CASP2ADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL26748554 | 0.80 | PAOX (0.57) | CASP2ADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL16250314 | 0.80 | RECQL (0.56) | RECQLGAAFAAHTSHRPAOX | |
| SCHEMBL13203022 | 0.80 | RECQL (0.54) | RECQLSLC6A5GAACASP2FAAH | |
| SCHEMBL15602555 | 0.79 | NAMPT (0.45) | SLC6A5CASP2ADRA1AFAAHTSHR | |
| SCHEMBL19477806 | 0.78 | RECQL (0.54) | RECQLGAAFAAHTSHRPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046426-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |