Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217371 | 0.81 | CA2 (0.48) | CA2CA1LMNAMAPK1HDAC3 | |
| SCHEMBL332832 | 0.78 | CA2 (0.66) | CA2CA1LMNAMAPK1TDP1 | |
| SCHEMBL684789 | 0.77 | TSHR (0.43) | CA2CA1LMNAMAPK1ALOX15 | |
| SCHEMBL28913174 | 0.77 | CA2 (0.58) | CA2CA1LMNAMAPK1 | |
| SCHEMBL28589749 | 0.77 | CA2 (0.63) | CA2CA1LMNAMAPK1TDP1 | |
| SCHEMBL6249435 | 0.77 | CA2 (0.63) | CA2CA1LMNAMAPK1TDP1 | |
| SCHEMBL755077 | 0.75 | CA2 (0.56) | CA2CA1LMNAMAPK1 | |
| SCHEMBL28087193 | 0.75 | CA2 (0.56) | CA2CA1LMNAMAPK1 | |
| SCHEMBL17713605 | 0.75 | CA2 (0.56) | CA2CA1LMNAMAPK1 | |
| SCHEMBL24153003 | 0.74 | CA2 (0.59) | CA2CA1MAPK1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046234-A1 | PROCESSES FOR THE PREPARATION OF ALPHA-HYDROXY ESTERS BY ESTERIFICATION OF ALPHA-HYDROXY ACIDS | KEMIN INDUSTRIES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |