Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.48 |
| ▸ | AHCY | P23526 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21139456 | 1.00 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL14075793 | 1.00 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13966427 | 1.00 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13975991 | 1.00 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6573811 | 1.00 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL24600719 | 0.90 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13400312 | 0.88 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13975989 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13966423 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL20580185 | 0.87 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | ECE1, RNASE1, RCE1 | PI4KA 1991/4885PI4K2B 2891/4885PI4K2A 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.