Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.67 |
| ▸ | HPGDS | O60760 | 3/20 | 0.64 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18845578 | 0.86 | HPGDS (0.83) | SCN10AHPGDSSSTR3 | |
| SCHEMBL18283950 | 0.86 | HPGDS (0.83) | SCN10AHPGDSSSTR3 | |
| SCHEMBL16577349 | 0.86 | SSTR3 (0.48) | SCN10AHPGDSSSTR3PRCP | |
| Hydrochloric Acid SCHEMBL18815647 | 0.85 | HPGDS (0.81) | SCN10AHPGDSSSTR3 | |
| Hydrochloric Acid SCHEMBL18815644 | 0.85 | HPGDS (0.81) | SCN10AHPGDSSSTR3 | |
| SCHEMBL2364211 | 0.78 | HPGDS (1.00) | SCN10AHPGDS | |
| SCHEMBL13070930 | 0.78 | SSTR3 (0.43) | SCN10AHPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL12302129 | 0.78 | SSTR3 (0.43) | SCN10AHPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL18213991 | 0.77 | PRCP (0.43) | SCN10AHPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL23080811 | 0.76 | HPGDS (0.47) | SCN10AHPGDSSSTR3PRCPPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070748-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070748-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | BTK, LYN, LCK | SCN10A 3037/4885HPGDS 820/4885SSTR3 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.