Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525754 | 1.00 | RAB9A (0.63) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL13903485 | 0.85 | MIF (0.62) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL23081589 | 0.85 | MIF (0.62) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL29201275 | 0.83 | RAB9A (0.62) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL21914766 | 0.83 | RAB9A (0.62) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL6443003 | 0.79 | MIF (0.76) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL21914676 | 0.77 | RAB9A (1.00) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL13401226 | 0.77 | RAB9A (1.00) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL21847106 | 0.77 | RAB9A (1.00) | RAB9AMIFSMN1; SMN2NPC1RECQL | |
| SCHEMBL13401228 | 0.76 | MIF (0.71) | RAB9AMIFSMN1; SMN2NPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046515-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-03-11 | — | — | WO | disclosed |