Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525756 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL29874891 | 0.87 | SMN1; SMN2 (0.52) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL30525730 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL23081339 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL15677682 | 0.79 | MEN1 (0.67) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL4816435 | 0.78 | MEN1 (0.64) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL12979304 | 0.78 | SMN1; SMN2 (0.68) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL4816442 | 0.78 | MEN1 (0.64) | MAPTMEN1KMT2AMIFRAB9A | |
| SCHEMBL23070193 | 0.78 | CYP1A2 (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL31309757 | 0.77 | MAPT (0.59) | MAPTMEN1KMT2AMIFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046515-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-03-11 | — | — | WO | disclosed |