Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525756 | 0.87 | MAPT (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12979304 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL23081599 | 0.87 | MAPT (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL26915494 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL30525730 | 0.77 | MAPT (0.55) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL23081339 | 0.77 | MAPT (0.55) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL15677682 | 0.77 | MEN1 (0.67) | SMN1; SMN2MAPTKMT2AMEN1MIF | |
| SCHEMBL4816435 | 0.76 | MEN1 (0.64) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4816442 | 0.76 | MEN1 (0.64) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL31309757 | 0.75 | MAPT (0.59) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132475-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2024-04-25 | — | — | US | disclosed |
| EP-4288417-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | Aurigene Oncology Limited (IN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167962-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132475-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS | MALT1, FKBP1B, FKBP1A | SMN1; SMN2 2342/4885ALDH1A1 2906/4885LMNA 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.