SCHEMBL23082001

SCHEMBL23082001

Brc1ccc(-c2cc(-c3ccccc3)cc(-c3ccccn3)n2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.47
CCR5 P51681 3/20 0.47
CCR8 P51685 3/20 0.47
SMN1; SMN2 Q16637 6/20 0.46
LMNA P02545 5/20 0.46
KDM4E B2RXH2 5/20 0.46
TP53 P04637 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALOX15 P16050 2/20 0.46
HTT P42858 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALPL P05186 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP19A1 P11511 1/20 0.45
HPGDS O60760 1/20 0.43
RAB9A P51151 5/20 0.43
PKM P14618 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4401831 0.86 MCL1 (0.56) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL3315795 0.86 MCL1 (0.56) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL19320191 0.86 MCL1 (0.56) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL3319965 0.86 MCL1 (0.56) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL23081979 0.86 HPGDS (0.54) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL24626281 0.86 HPGDS (0.54) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL30943430 0.85 CCR1 (0.55) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL29505007 0.85 CCR1 (0.55) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL30943427 0.85 CCR1 (0.55) CCR1CCR5CCR8SMN1; SMN2LMNA
SCHEMBL21849866 0.85 CCR1 (0.55) CCR1CCR5CCR8SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021066397-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-04-08 WO disclosed
WO-2021045460-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-03-11 WO disclosed