SCHEMBL2308261

SCHEMBL2308261

Cc1ccc(N(c2ccccc2)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
CYP2C19 P33261 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 3/20 0.39
ACHE P22303 2/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
APP P05067 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
S1PR1 P21453 1/20 0.37
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13242030 0.94 MAPT (0.40) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL2310644 0.94 ALDH1A1 (0.48) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL14163838 0.94 ALDH1A1 (0.48) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL26280939 0.94 ALDH1A1 (0.48) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL295453 0.94 ALDH1A1 (0.48) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL7764832 0.92 ALDH1A1 (0.44) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL10066013 0.92 ALDH1A1 (0.44) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL14186200 0.92 ALDH1A1 (0.44) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL7765887 0.92 ALDH1A1 (0.44) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL7760602 0.91 MAPT (0.40) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221744-A1 LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-18 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8008507-B2 Fluorescent diketopyrrolopyrroles BASF SE Ludwigshafen (DE) 2011-08-30 US disclosed
US-8008507-B2 Fluorescent diketopyrrolopyrroles BASF SE Ludwigshafen (DE) 2011-08-30 US disclosed
EP-2000855-B1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH CO LTD (JP) 2011-08-03 EP disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-20090214968-A1 MIXTURE OF BISAMINE COMPOUNDS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-27 US disclosed
US-20090214968-A1 MIXTURE OF BISAMINE COMPOUNDS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-27 US disclosed
US-20090214968-A1 MIXTURE OF BISAMINE COMPOUNDS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-27 US disclosed
EP-1817392-B1 FLUORESCENT DIKETOPYRROLOPYRROLES CIBA HOLDING INC (CH) 2009-01-07 EP disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed
EP-2000855-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080217581-A1 Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance CIBA CORPORATION 2008-09-11 US disclosed
US-20080217581-A1 Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance CIBA CORPORATION 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080217581-A1 Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance TYR, MC1R, IK ALDH1A1 1112/4885MAPT 1123/4885CYP2C19 847/4885
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 ALDH1A1 1243/4885MAPT 1195/4885CYP2C19 980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.