⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493591 | 0.79 | — | — | |
| SCHEMBL14690996 | 0.76 | — | — | |
| SCHEMBL387713 | 0.74 | — | — | |
| SCHEMBL14889954 | 0.70 | — | — | |
| SCHEMBL6761113 | 0.70 | — | — | |
| SCHEMBL8171947 | 0.70 | — | — | |
| SCHEMBL79002 | 0.70 | — | — | |
| SCHEMBL4731479 | 0.70 | — | — | |
| SCHEMBL13651723 | 0.67 | — | — | |
| SCHEMBL16473 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065062-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | claimed |
| US-20120035051-A1 | Novel Heterocyclic Thiosubstituted Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-09 | — | — | US | claimed |
| US-7582638-B2 | Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors | ELI LILLY AND COMPANY (US) | 2009-09-01 | — | — | US | claimed |
| US-20080275056-A1 | With improved potency and greater bioavailability; 1-{1-[1-(1-Methyl-cyclopropanecarbonyl)-piperidin-4-yloxy]-isoquinolin-4-yl}-3-[5-(1-methyl-cyclopropyl)-2-p-tolyl-2H-pyrazol-3-yl]-urea; antimetastasis and antineoplastic agents, rheumatoid arthritis | ELI LILLY AND COMPANY | 2008-11-06 | — | — | US | claimed |
| EP-1943244-A1 | PYRAZOLE-ISOQUINOLINE UREA DERIVATIVES AS P38 KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007053346-A1 | PYRAZOLE-ISOQUINOLINE UREA DERIVATIVES AS P38 KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2007-05-10 | — | — | WO | claimed |
| WO-1999033790-A1 | INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-08 | — | — | WO | claimed |
| US-4840969-A | APPLYING AS INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| EP-0101926-B1 | AZOLYL-KETO-ENAMINES | BAYER AG (DE) | 1986-09-03 | — | — | EP | claimed |
| EP-0160931-A2 | Azolylvinyl ethers | BAYER AG (DE) | 1985-11-13 | — | — | EP | claimed |
| EP-0101926-A1 | Azolyl-keto-enamines | BAYER AG (DE) | 1984-03-07 | — | — | EP | claimed |
| CN-108137538-B | Triazole derivatives, intermediates thereof and their use as fungicides | 拜耳作物科学股份公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-3738959-A1 | PREPARATION OF 6-PHENOXY-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer AG (DE) | 2020-11-18 | — | — | EP | disclosed |
| WO-2020120284-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-18 | — | — | WO | disclosed |
| EP-3666759-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer Aktiengesellschaft (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-0016323-B1 | 1-ALLYLTRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| EP-0057357-A2 | Plant growth stunting agent | BAYER AG (DE) | 1982-08-11 | — | — | EP | disclosed |
| US-4315764-A | FUNGICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| EP-0016323-A1 | 1-Allyltriazole derivatives, process for their preparation and their use as plant protecting agents | BAYER AG (DE) | 1980-10-01 | — | — | EP | disclosed |
| EP-0015387-A2 | 1-Vinyltriazole derivatives, process for their preparation and their use as growth regulating agents and fungicides | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |