Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.71 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23090386 | 0.84 | ABCB1 (0.61) | DHODHKMT2AMEN1RAB9ALMNA | |
| SCHEMBL23090382 | 0.83 | DHODH (1.00) | DHODHNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23090409 | 0.82 | DHODH (0.63) | DHODHNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23090367 | 0.82 | DHODH (1.00) | DHODHNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23090385 | 0.80 | DHODH (0.70) | DHODHKMT2AMEN1RAB9ALMNA | |
| SCHEMBL23090379 | 0.79 | DHODH (0.78) | DHODHNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23090415 | 0.79 | MEN1 (0.62) | DHODHKMT2AMEN1RAB9ALMNA | |
| SCHEMBL23090416 | 0.78 | DHODH (1.00) | DHODHNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23090368 | 0.74 | DHODH (0.53) | DHODHKMT2AMEN1RAB9ALMNA | |
| SCHEMBL23090366 | 0.74 | DHODH (0.57) | DHODHKMT2AMEN1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | ZC3HAV1, MAVS, ZC3HAV1L | DHODH 344/4885NR1H4 3648/4885KMT2A 3836/4885 |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | ZC3HAV1, MAVS, ZC3HAV1L | DHODH 344/4885NR1H4 3648/4885KMT2A 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.