Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 8/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093142 | 0.96 | SMN1; SMN2 (0.47) | SMN1; SMN2CNR2PLK1TP53TSHR | |
| SCHEMBL23093086 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL23092995 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL5869497 | 0.86 | CNR2 (0.44) | CNR2PLK1PLK3TRPM2PPARG | |
| SCHEMBL23093133 | 0.83 | CNR2 (0.43) | CNR2PLK1PLK3TSHRKCNQ4 | |
| SCHEMBL19930251 | 0.83 | PPARA (0.44) | CNR2TSHRPPARAKCNQ4KCNQ5 | |
| SCHEMBL5162892 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2APPARGKCNQ4 | |
| SCHEMBL23093006 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL23093001 | 0.82 | KCNQ4 (0.39) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL5562681 | 0.82 | KMT2A (0.47) | CNR2PLK1PLK3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050547-A1 | MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-03-18 | — | — | WO | disclosed |